2-8-17 NOTE: I feel good. My quality of life is high. The myeloma cancer markers, however, reveal a low speed relapse. MM always finds a way …
So, Dr. B and I have decided to add Velcade (Bortezomib) to the Darzalex (Daratumumab) I am currently taking. Unfortunately, the momentum of its effectiveness was interrupted by last summer’s pneumonia. I was off treatment for three months. Since October, I have been taking it twice a month. I am relatively stable but the trend of my M-spike is up.
The new regimen has me taking Darzlex once a month, Velcade weekly, and 12 mg of dexamethasone weekly. I also receive IVIG once a month and Zometa (a bone strengthener) once every three months. The graph to the left represents the new baseline from which we are proceeding.
Persistent hip pain required X-rays in October, which we followed up on at the end of January with an MRI.
The image revealed bone involvement related to myeloma. Lesions, consistent with the disease are prevalent in the hip and throughout my pelvic area and lower spine. At this time, intervention with radiation is not necessary. We are doing most of what can be done. If the new regimen proves to be effective, further bone erosion should be minimized and healing can occur.
Blood labs: CBC, Chem Panel, Serum Free Light Chain Assay, and Serum Protein Electrophoresis on day 22 of every 28 day cycle.
Clinic with oncologist once each month to review lab results.
I will update the results from labs taken monthly on three indices:
M-spike, the clearest indicator of cancer activity.
Creatinine, which shows how my kidneys are faring as myeloma can cause kidney problems.
Hemogloblin, for anemia, as it is a symptom common to MM patients and present in me from the get-go.
Baseline M-spike g/dL Creatinine mg/dL Hemoglobin g/dL
1-30-17 2.3 😦 0.90 normal 9.1 😦
2-20-17 1.9 🙂 0.84 normal 9.0 😦
3-20-17 1.7 🙂 0.88 normal 9.3 😦
4-17-17 1.7 🙂 0.80 normal 9.8 😦
5-15-17 1.8 hmmm … 0.84 normal 9.5 😦
6-12-17 1.9 sigh … 0.92 normal 9.8 😦
7-10-17 1.8 okish 0.87 normal 9.8 😦
8-7-17 1.8 0kish 0.84 normal 10.4 low
9-5-17 2.0 less okish 0.90 normal 10.7 low
8-14-17 NOTE: I feel good. My quality of life is high. I do what I want: garden, golf, hike, and chase the grandkids. The MM is stable.
Aspirin 81mg daily
Acyclovir 400mg twice a day
Magnesium and Zinc, 400mg & 15mg daily
Calcium + D3, 400mg & 500 IU twice a day
Fish Oil Omega-3, 1000mg twice a day
B6, Folic Acid, B12, 2mg & 800mcg & 1000mcg twice a day